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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
13.94
Human Site:
T228
Identified Species:
27.88
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
T228
R
K
A
E
G
K
A
T
S
T
T
E
L
P
P
Chimpanzee
Pan troglodytes
XP_511742
777
85768
S228
K
A
E
G
K
A
T
S
T
T
E
L
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
T228
R
K
A
E
G
K
A
T
S
T
T
E
L
P
P
Dog
Lupus familis
XP_540486
782
86005
E232
G
K
V
S
S
T
T
E
L
P
P
E
Y
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
S228
K
K
A
E
G
K
A
S
S
T
T
E
L
P
P
Rat
Rattus norvegicus
Q9JJ50
776
86228
A228
K
K
A
E
G
K
A
A
S
T
T
E
L
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
A228
K
K
G
E
G
K
S
A
S
G
P
E
L
P
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
G226
R
P
T
S
G
S
G
G
A
K
S
G
P
R
P
Honey Bee
Apis mellifera
XP_393989
830
92147
I227
N
K
P
S
T
A
Q
I
K
E
A
D
L
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
S225
E
K
L
Q
G
K
S
S
S
T
N
D
L
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
Q130
V
A
F
K
N
D
S
Q
L
N
Y
V
A
K
V
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
A225
R
V
D
D
G
C
Y
A
K
L
T
D
K
G
G
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
13.3
100
13.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
60
N.A.
N.A.
20
20
N.A.
46.6
P-Site Similarity:
100
33.3
100
13.3
N.A.
100
93.3
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
33.3
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
34
0
0
17
34
25
9
0
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
9
0
0
0
0
0
25
0
0
9
% D
% Glu:
9
0
9
42
0
0
0
9
0
9
9
50
0
0
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
9
67
0
9
9
0
9
0
9
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
34
67
0
9
9
50
0
0
17
9
0
0
9
9
0
% K
% Leu:
0
0
9
0
0
0
0
0
17
9
0
9
59
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
9
17
0
17
67
50
% P
% Gln:
0
0
0
9
0
0
9
9
0
0
0
0
0
0
0
% Q
% Arg:
34
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
0
25
9
9
25
25
50
0
9
0
0
0
0
% S
% Thr:
0
0
9
0
9
9
17
17
9
50
42
0
0
0
9
% T
% Val:
9
9
9
0
0
0
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _